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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EGR2 All Species: 10.3
Human Site: Y75 Identified Species: 25.19
UniProt: P11161 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11161 NP_000390.2 476 50302 Y75 K R S L D L P Y P S S F A P V
Chimpanzee Pan troglodytes XP_001165856 475 50152 Y74 K R S L D L P Y P S S F A P V
Rhesus Macaque Macaca mulatta XP_001092603 475 50169 Y74 K R S L D L P Y P S S F A P V
Dog Lupus familis XP_536361 472 49945 L71 M T G E K R S L D L P Y P S S
Cat Felis silvestris
Mouse Mus musculus P08152 470 49801 D63 G D G M I N I D M T G E K R P
Rat Rattus norvegicus P51774 470 49831 D63 G D G M I N I D M T G E K R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509408 291 31482
Chicken Gallus gallus
Frog Xenopus laevis Q08427 421 46362 E22 S F V H Q I P E G F Y P G E D
Zebra Danio Brachydanio rerio Q05159 412 45134 L13 L E K A P V S L G G F V H P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13360 604 62491 S197 H P H Q M L I S P N S H N H G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.1 96.2 N.A. 89 89.2 N.A. 39.7 N.A. 59.6 63 N.A. 21.5 N.A. N.A. N.A.
Protein Similarity: 100 99.7 99.5 97 N.A. 92.4 92.4 N.A. 45.7 N.A. 67.4 73.5 N.A. 35.2 N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 0 0 N.A. 0 N.A. 6.6 6.6 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 13.3 13.3 N.A. 0 N.A. 13.3 20 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 30 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 0 30 0 0 20 10 0 0 0 0 0 10 % D
% Glu: 0 10 0 10 0 0 0 10 0 0 0 20 0 10 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 10 10 30 0 0 0 % F
% Gly: 20 0 30 0 0 0 0 0 20 10 20 0 10 0 10 % G
% His: 10 0 10 10 0 0 0 0 0 0 0 10 10 10 0 % H
% Ile: 0 0 0 0 20 10 30 0 0 0 0 0 0 0 0 % I
% Lys: 30 0 10 0 10 0 0 0 0 0 0 0 20 0 0 % K
% Leu: 10 0 0 30 0 40 0 20 0 10 0 0 0 0 10 % L
% Met: 10 0 0 20 10 0 0 0 20 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 20 0 0 0 10 0 0 10 0 0 % N
% Pro: 0 10 0 0 10 0 40 0 40 0 10 10 10 40 20 % P
% Gln: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 30 0 0 0 10 0 0 0 0 0 0 0 20 0 % R
% Ser: 10 0 30 0 0 0 20 10 0 30 40 0 0 10 10 % S
% Thr: 0 10 0 0 0 0 0 0 0 20 0 0 0 0 0 % T
% Val: 0 0 10 0 0 10 0 0 0 0 0 10 0 0 30 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 30 0 0 10 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _